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Nutr Clin Pract ; 39(2): 373-384, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38030585

ABSTRACT

Vitamin A imbalance during pregnancy and lactation is a global public health concern with potentially negative consequences for fetuses and neonates. Inadequate vitamin A intake during this critical period can lead to anemia, weakened immune function, night blindness, and increased susceptibility to infections. Conversely, excessive intake of vitamin A can result in birth defects, hypercalcemia, and psychiatric symptoms. This review aims to identify risk factors contributing to vitamin A deficiency in pregnant women and its impact on maternal, fetal, and neonatal outcomes. It also examines the effects of high-dose vitamin A supplementation during pregnancy on offspring health. By analyzing existing literature and recommendations, the review emphasizes the significance of vitamin A in the development of various body systems and organs. It provides a comprehensive overview of the effects of vitamin A during pregnancy and lactation, encompassing deficiencies, excessive intake, and supplementation guidelines. The need for further research in this field is highlighted. In conclusion, maintaining a balanced vitamin A status is crucial during pregnancy to promote better outcomes for fetuses and newborns. Effective monitoring and intervention strategies are essential to address vitamin A deficiency and excess in pregnant women, thereby improving fetal and neonatal health.


Subject(s)
Pregnancy Complications , Vitamin A Deficiency , Vitamin D Deficiency , Infant, Newborn , Female , Pregnancy , Humans , Vitamin A/therapeutic use , Vitamins/therapeutic use , Vitamin A Deficiency/drug therapy , Vitamin A Deficiency/epidemiology , Pregnancy Complications/epidemiology , Lactation , Dietary Supplements
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